Industry Collaborations

Why the SAGC?

Best NGS Economics in Australia

The SAGC is the only NCRIS-Bioplatforms supported core facility with the MGI DNBSEQ-T7, capable of sequencing 60 whole genomes per day, and enabling STOmics (spatial transcriptomics).

Complete Toolkit from 10X Genomics

The SAGC is 1 of only 3 reference centres for 10X Genomics in Australia – a leader in spatial and single cell transcriptomics (we offer Chromium, Visium + CytAssist and Xenium).

Dedicated Bioinformatics Team

There to offer support from basic off-the-shelf tools to complex analysis, custom tools and data visualisations.

Key Applications Supporting Drug Discovery

Single Cell Sequencing (scRNA-seq): understanding differential gene expression by cell-type can help inform targets and drug candidates in a variety of ways:

Improve disease understanding
Provide insights on cell-type-specific activity
Better understand cancer development
Elucidate Off-target effects and heterogeneous responses
Identify clinically relevant targets and biomarkers

The SAGC offers both microfluidic-based and plate-based combinatorial barcoding technologies as a service. Read More

Van de Sande, B., Lee, J.S., Mutasa-Gottgens, E. et al. Applications of single-cell RNA sequencing in drug discovery and development. Nat Rev Drug Discov 22, 496–520 (2023).

Spatial Transcriptomics (ST): the addition of spatiotemporal information to gene expression data is enabling researchers to better identify potential drug targets and resistance mechanisms.

Whole and targeted transcriptome mapping
Capture dynamics of various pathologies
Spatial cell distribution in pathogenesis of diseases
Visualize biomarkers with spatial interactions
See tumour transcriptomes in their native architecture
Assist in early disease diagnosis and prognosis

Zhang, L., Chen, D., Song, D. et al. Clinical and translational values of spatial transcriptomics. Sig Transduct Target Ther 7, 111 (2022).

Support for Australian Biotech

The SAGC is part of the Health Innovation Ecosystem in SA

The precinct supports 2000 researchers and 10,000+ staff.

Book a consultation to explore how our genomics capabilities can support your next project.