Spatial Transcriptomics
Spatial transcriptomics is the study of gene expression patterns within the context of tissue architecture and can provide a more complete understanding of cell-cell interactions. It is a powerful tool for anyone interested in understanding the complexity of biological systems and tissue organization at high resolution.
Single cell spatial imaging with 10x Genomics Xenium Analyzer
Interested in trying out Xenium?
Learn what Xenium can do for you in this data demo of mouse brain tissue analysis, including:
- Automatic cell clustering in a spatial context
- Exquisite subcellular resolution of individual transcripts
- Easy and intuitive tissue-scale comparisons
- Seamless panning, zooming, and analysis of your entire tissue section
Visium & Visium HD
Whole transcriptome mapping within morphological context of complex tissue samples
- Specialised slides contain spatially barcoded spots giving you high-resolution from standard tissue sectioning and staining.
- Compatible with both FFPE and fresh frozen tissue samples.
- Whole transcriptome analysis – no need to select targets or specific region of interest.
- CytAssist enabled to allow transfer of tissues from archived slides.
Stereo-seq (SpaTial Enhanced Resolution Omics-Sequencing)
Whole transcriptomics for discovery applications (range of 1000-2000 genes/cell) leverages in situ mRNA capture and cDNA sequencing with barcoded spatial coordinates to create a spatial transcriptomic profile of the tissue section for analysis.
- Subcellular spatial localization of mRNA
- Chip design ~320M spatially barcoded spots/cm2
- Spot size = 200 nm diameter
- Range of field size to accommodate larger tissue samples (up to 13 cm x 13cm)
STOmics Stereo-seq OMNI for FFPE Samples
- Total RNA and Microbial RNA
- Species Agnostic
- Single-cell resolution
Xenium In Situ
Targeted gene expression and protein quantification at subcellular resolution
Xenium is an end-to-end platform that enables high-throughput subcellular mapping of RNA targets.
- Menu of off-the-shelf gene panels + order 100 custom add-on genes
- Compatible with fresh frozen (FF) and formalin-fixed, paraffin-embedded (FFPE) tissues
- Microscopy based read-out (no NGS), allows H&E post-run
- Single molecule RNA and Protein targets (subcellular resolution)
