Spatial Transcriptomics
Spatial transcriptomics is the study of gene expression patterns within the context of tissue architecture and can provide a more complete understanding of cell-cell interactions. It is a powerful tool for anyone interested in understanding the complexity of biological systems and tissue organization at high resolution.
DAPI Stain
Gene Expression Heat Map
Visium & Visium HD
Whole transcriptome mapping within morphological context of complex tissue samples
- Specialised slides contain spatially barcoded spots giving you high-resolution from standard tissue sectioning and staining.
- Compatible with both FFPE and fresh frozen tissue samples.
- Whole transcriptome analysis – no need to select targets or specific region of interest.
- CytAssist enabled to allow transfer of tissues from archived slides.
Stereo-seq (SpaTial Enhanced Resolution Omics-Sequencing)
Whole transcriptomics for discovery applications (range of 1000-2000 genes/cell) leverages in situ mRNA capture and cDNA sequencing with barcoded spatial coordinates to create a spatial transcriptomic profile of the tissue section for analysis.
- Subcellular spatial localization of mRNA
- Chip design ~320M spatially barcoded spots/cm2
- Spot size = 200 nm diameter
- Range of field size to accommodate larger tissue samples (up to 13 cm x 13cm)
STOmics Stereo-seq OMNI for FFPE Samples
- Total RNA and Microbial RNA
- Species Agnostic
- Single-cell resolution
Xenium In Situ
Targeted gene expression and protein quantification at subcellular resolution
Xenium is an end-to-end platform that enables high-throughput subcellular mapping of RNA targets.
- Menu of off-the-shelf gene panels + order 100 custom add-on genes
- Compatible with fresh frozen (FF) and formalin-fixed, paraffin-embedded (FFPE) tissues
- Microscopy based read-out (no NGS), allows H&E post-run
- Single molecule RNA and Protein targets (subcellular resolution)
